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Thursday, May 6, 2004


This is to scare you
A sample of the writing I've been doing which has been keeping me from OB (rightfully so):

Flavoenzymes catalyze a variety of chemical reactions, but we will focus on oxidations with molecular oxygen. Flavoprotein oxidases are a useful natural system to mimic with imprinted polymers because they will oxidize a substrate without an external cofactor. The catalytic system involves two half-reactions where the substrate is oxidized by the flavin, and the flavin is subsequently re-oxidized by molecular oxygen. Vanillyl-alcohol oxidase8 (VAO) serves as a good model for the flavoenzyme oxidases because it is the most studied and well known system, and it can oxidize a variety of substrates. There are about 200 crystal structures available in the Protein Data Bank for FAD and FMN dependant proteins. The common features of all of these enzymes were reported in a review by Mattevi9 which highlighted the orientation about the flavin in the catalytic site.

Not that anybody actually wanted to read this stuff.

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